LRRC18

Across TCGA patient cohorts, LRRC18 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,480 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC18-associated proteins across cancer lineages are ADA2, RCSD1, and SEPTIN1_S206. Each is linked with LRRC18 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRRC18-to-partner and partner-to-LRRC18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC18 versus ADA2 in CCRCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC18→partner) and Y-score (partner→LRRC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ADA2 →	+0.586	+0.542	<.001	<.001	3	7
HNSC	RCSD1 →	+0.627	+1.038	<.001	<.001	3	7
GBM	SEPTIN1_S206 →	+1.052	+0.770	<.001	<.001	3	7
HNSC	TRAF3IP3 →	+0.719	+1.080	<.001	<.001	3	7
LSCC	WDFY4 →	+0.657	+1.029	<.001	<.001	3	7
GBM	DOCK2 →	+0.692	+0.809	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,480 associations by consensus.

LRRC18 vs ADA2 — CCRCC

Explore this scatter interactively →