Across TCGA patient cohorts, LRRC14B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,054 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LRRC14B-associated GO terms across cancer lineages are Obsolete histone modification, Nucleus organization, and Negative regulation of gene expression, epigenetic. Each is linked with LRRC14B in more than 18 cancer types. Because this analysis shows association rather than direction, both LRRC14B-to-partner and partner-to-LRRC14B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC14B→partner) and Y-score (partner→LRRC14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Obsolete histone modification →	+0.038	+0.161	<.001	<.001	3	19
STAD	Nucleus organization →	+0.035	+0.165	<.001	<.001	3	18
THYM	Negative regulation of gene expression, epigenetic →	+0.053	+0.765	<.001	<.001	3	18
THYM	Regulation of stem cell population maintenance →	+0.046	+0.590	<.001	<.001	3	17
UCS	Regulation of DNA biosynthetic process →	+0.039	+1.636	<.001	.004	3	17
STAD	Regulation of translational initiation →	+0.066	+0.239	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,054 associations by consensus.

Exploration

LRRC14B survival (RNA) · tumor vs normal (RNA) · all LRRC14B data types