Across TCGA cell cohorts, LRRC14B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,648 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC14B-associated GO terms across cancer lineages are Negative regulation of mRNA processing, Regulation of DNA-templated transcription initiation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with LRRC14B in more than 9 cancer types. Because this analysis shows association rather than direction, both LRRC14B-to-partner and partner-to-LRRC14B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC14B→partner) and Y-score (partner→LRRC14B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Negative regulation of mRNA processing →	+0.096	+0.041	<.001	.002	3	9
LIVER	Regulation of DNA-templated transcription initiation →	+0.056	+0.066	.006	.005	2	10
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.051	.007	.006	3	9
LARGE_INTESTINE	Regulation of transcription initiation by RNA polymerase II →	+0.048	+0.092	.001	.004	2	10
LIVER	Regulation of double-strand break repair →	+0.067	+0.074	.007	.005	3	8
URINARY_TRACT	RNA localization →	+0.068	+0.047	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,648 associations by consensus.

Exploration

LRRC14B survival (RNA) · tumor vs normal (RNA) · all LRRC14B data types