Across TCGA pan-cancer cohorts, LRRC10B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LRRC10B data layer compared with 24 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher LRRC10B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC10B expression acts as an unfavorable survival marker.

ACC and UCEC are the cancer types where LRRC10B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.010	0.667	<.001	45	view →
UCEC	OS	Median	IV	0.308	0.748	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LRRC10B tumor-vs-normal RNA expression · all LRRC10B data types