LRP2BP

Across TCGA patient cohorts, LRP2BP protein abundance is significantly associated with the RNA expression of many other genes, with 3,333 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRP2BP-associated genes across cancer lineages are FN1, GFPT2, and PRSS23. Each is linked with LRP2BP in more than 2 cancer types. Because this analysis shows association rather than direction, both LRP2BP-to-partner and partner-to-LRP2BP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRP2BP versus FN1 in PDAC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP2BP→partner) and Y-score (partner→LRP2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FN1 →	+1.721	+0.803	.002	.002	3	2
PDAC	GFPT2 →	+1.181	+0.803	.001	.002	3	2
PDAC	PRSS23 →	+0.890	+0.803	.004	.002	3	2
GBM	ACSL1 →	+0.996	+0.592	<.001	<.001	3	2
PDAC	CTNNB1 →	+0.517	+0.952	.002	.008	3	2
GBM	TPST1 →	+0.671	+0.486	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,333 associations by consensus.

LRP2BP vs FN1 — PDAC

Explore this scatter interactively →