LRP2BP

Across TCGA cell cohorts, LRP2BP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,879 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRP2BP-associated GO terms across cancer lineages are Microtubule organizing center organization, DNA biosynthetic process, and Translesion synthesis. Each is linked with LRP2BP in more than 10 cancer types. Because this analysis shows association rather than direction, both LRP2BP-to-partner and partner-to-LRP2BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule organizing center organization grouped by LRP2BP-low versus LRP2BP-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP2BP→partner) and Y-score (partner→LRP2BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Microtubule organizing center organization →	+0.089	+0.725	<.001	<.001	3	11
STOMACH	DNA biosynthetic process →	+0.082	+0.566	<.001	.002	3	11
LUNG_SCLC	Translesion synthesis →	+0.095	+0.733	.001	<.001	3	11
LUNG_SCLC	DNA synthesis involved in DNA replication →	+0.099	+0.638	<.001	<.001	3	11
URINARY_TRACT	Subtelomeric heterochromatin formation →	+0.115	+0.377	<.001	<.001	3	11
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.114	+0.256	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,879 associations by consensus.

Microtubule organizing center organization by LRP2BP expression — STOMACH

Explore this box plot interactively →