LRP12

Across TCGA cell cohorts, LRP12 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,737 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRP12-associated GO terms across cancer lineages are Positive regulation of early endosome to late endosome transport, Vesicle cargo loading, and Regulation of early endosome to late endosome transport. Each is linked with LRP12 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRP12-to-partner and partner-to-LRP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of early endosome to late endosome transport grouped by LRP12-low versus LRP12-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP12→partner) and Y-score (partner→LRP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of early endosome to late endosome transport →	+0.125	+2.825	.009	<.001	3	12
BONE	Vesicle cargo loading →	+0.129	+1.319	<.001	.001	3	12
LUNG_NSCLC_LUAD	Regulation of early endosome to late endosome transport →	+0.080	+0.995	.001	<.001	3	11
SOFT_TISSUE	Positive regulation of extracellular matrix organization →	+0.158	+1.233	<.001	<.001	3	11
BONE	Positive regulation of intracellular transport →	+0.079	+1.331	.003	.006	3	11
UPPER_AERODIGESTIVE_TRACT	Response to oscillatory fluid shear stress →	+0.149	+1.230	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,737 associations by consensus.

Positive regulation of early endosome to late endosome transport by LRP12 expression — OESOPHAGUS

Explore this box plot interactively →