Across TCGA pan-cancer cohorts, LRP10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated LRP10 data layer compared with 24 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LRP10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LRP10 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where LRP10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	II,III,IV	1.000	0.903	.021	15	view →
PDAC	DFS	Quartile	All	0.552	0.253	.019	10	view →
LUAD	DFS	Median	II,III,IV	0.373	0.613	.029	8	view →
GBM	OS	Median	All	0.522	0.232	.024	4	view →
CCRCC	OS	Median	III,IV	0.202	1.000	.022	4	view →
LSCC	OS	Median	All	0.758	0.866	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: LRP10 tumor-vs-normal RNA expression · all LRP10 data types