Across TCGA patient cohorts, LRP10 protein abundance is significantly associated with the RNA expression of many other genes, with 9,105 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LRP10-associated genes across cancer lineages are APH1B, MYEF2, and AGO3. Each is linked with LRP10 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRP10-to-partner and partner-to-LRP10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRP10→partner) and Y-score (partner→LRP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	APH1B →	-0.729	-0.404	<.001	<.001	3	4
HNSC	MYEF2 →	-1.196	-0.394	<.001	<.001	3	4
GBM	AGO3 →	-0.524	-0.379	<.001	<.001	3	4
BRCA	ARNT2 →	-0.988	-0.324	.001	.004	3	4
BRCA	MPHOSPH9 →	-0.608	-0.341	<.001	.004	3	4
BRCA	ZKSCAN2 →	-0.441	-0.311	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,105 associations by consensus.

Exploration

LRP10 survival (RNA) · tumor vs normal (RNA) · all LRP10 data types