LRMDA

Across TCGA patient cohorts, LRMDA protein abundance is significantly associated with the RNA expression of many other genes, with 16,900 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRMDA-associated genes across cancer lineages are RENBP, MS4A6A, and LY86. Each is linked with LRMDA in more than 5 cancer types. Because this analysis shows association rather than direction, both LRMDA-to-partner and partner-to-LRMDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRMDA versus RENBP in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRMDA→partner) and Y-score (partner→LRMDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RENBP →	+0.903	+0.452	<.001	<.001	3	6
GBM	MS4A6A →	+1.204	+0.753	<.001	<.001	3	6
GBM	LY86 →	+0.808	+0.655	<.001	<.001	3	6
GBM	TLR2 →	+1.076	+0.681	<.001	<.001	3	6
LSCC	PLCB2 →	+0.798	+0.493	<.001	<.001	3	6
UCEC	PARVG →	+0.845	+0.331	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,900 associations by consensus.

LRMDA vs RENBP — UCEC

Explore this scatter interactively →