LRMDA

Across TCGA cell cohorts, LRMDA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,125 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRMDA-associated GO terms across cancer lineages are Protein folding, G1 to G0 transition involved in cell differentiation, and Endosome transport via multivesicular body sorting pathway. Each is linked with LRMDA in more than 9 cancer types. Because this analysis shows association rather than direction, both LRMDA-to-partner and partner-to-LRMDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by LRMDA-low versus LRMDA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRMDA→partner) and Y-score (partner→LRMDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein folding →	+0.064	+1.694	<.001	<.001	3	9
SKIN	G1 to G0 transition involved in cell differentiation →	+0.894	+2.107	<.001	<.001	3	9
SKIN	Endosome transport via multivesicular body sorting pathway →	+0.078	+2.220	<.001	<.001	3	9
SKIN	Energy derivation by oxidation of organic compounds →	+0.054	+1.851	.005	.004	2	10
LUNG_NSCLC_LUSC	Carbohydrate derivative catabolic process →	+0.070	+2.361	<.001	<.001	3	8
BONE	Sphingolipid catabolic process →	+0.149	+1.521	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,125 associations by consensus.

Protein folding by LRMDA expression — BONE

Explore this box plot interactively →