Across TCGA cell cohorts, LRIT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,948 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRIT3-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, RNA catabolic process, and Regulation of alternative mRNA splicing, via spliceosome. Each is linked with LRIT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both LRIT3-to-partner and partner-to-LRIT3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIT3→partner) and Y-score (partner→LRIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear-transcribed mRNA catabolic process →	+0.064	+0.244	.001	.005	3	11
BONE	RNA catabolic process →	+0.078	+0.316	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of alternative mRNA splicing, via spliceosome →	+0.076	+0.135	<.001	<.001	3	10
SOFT_TISSUE	mRNA splice site recognition →	+0.112	+0.094	<.001	.006	2	11
BONE	Nucleic acid catabolic process →	+0.066	+0.253	<.001	<.001	3	9
BONE	Negative regulation of DNA-templated transcription, elongation →	+0.127	+0.284	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,948 associations by consensus.

Exploration

LRIT3 survival (RNA) · tumor vs normal (RNA) · all LRIT3 data types