Across TCGA cell cohorts, LRIT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 933 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRIT2-associated GO terms across cancer lineages are Protein localization to paranode region of axon, Activation of blood coagulation via clotting cascade, and Epithelial cell development. Each is linked with LRIT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRIT2-to-partner and partner-to-LRIT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIT2→partner) and Y-score (partner→LRIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein localization to paranode region of axon →	+0.567	+0.264	<.001	<.001	3	4
LARGE_INTESTINE	Activation of blood coagulation via clotting cascade →	-0.209	-0.445	<.001	<.001	3	4
LUNG_SCLC	Epithelial cell development →	-0.054	-0.207	.001	.001	3	4
LUNG_SCLC	Adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway →	+1.365	+0.240	<.001	.001	3	3
LARGE_INTESTINE	Negative regulation of endothelial cell proliferation →	-0.117	-0.288	<.001	.002	3	3
LARGE_INTESTINE	Catechol-containing compound catabolic process →	+0.125	+0.371	.006	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 933 associations by consensus.

Exploration

LRIT2 survival (RNA) · tumor vs normal (RNA) · all LRIT2 data types