LRIT1

Across TCGA cell cohorts, LRIT1 RNA expression is significantly associated with the mutation status of many other genes, with 358 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRIT1-associated genes across cancer lineages are MYH9, DDX54, and ATG9A. Each is linked with LRIT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRIT1-to-partner and partner-to-LRIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH9 grouped by LRIT1-low versus LRIT1-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIT1→partner) and Y-score (partner→LRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYH9 →	+3.362	+0.021	.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	DDX54 →	+3.285	+0.028	.006	.004	3	3
BLOOD_Leukemia	ATG9A →	+5.269	+0.046	<.001	<.001	3	2
BLOOD_Lymphoma	MCM9 →	+5.209	+0.016	.005	<.001	3	2
BREAST	SZT2 →	+1.949	+0.009	.005	.001	3	2
STOMACH	MROH1 →	+3.017	+0.026	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

MYH9 by LRIT1 expression — BLOOD_Leukemia

Explore this box plot interactively →