LRIG3

Across TCGA patient cohorts, LRIG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,535 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LRIG3-associated proteins across cancer lineages are CCT8_S537, MRPL16, and NDUFAF4. Each is linked with LRIG3 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRIG3-to-partner and partner-to-LRIG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRIG3 versus CCT8_S537 in BRCA, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG3→partner) and Y-score (partner→LRIG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCT8_S537 →	-0.675	-0.675	.003	.009	3	5
BRCA	MRPL16 →	-0.406	-1.008	<.001	<.001	3	4
OV	NDUFAF4 →	-0.405	-0.756	.001	.002	3	4
LSCC	STK10 →	-0.330	-0.664	<.001	<.001	3	4
PDAC	STX11 →	-0.747	-0.607	<.001	<.001	3	4
CCRCC	DMXL2 →	-0.249	-0.632	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,535 associations by consensus.

LRIG3 vs CCT8_S537 — BRCA

Explore this scatter interactively →