LRIG3

Across TCGA cell cohorts, LRIG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,172 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRIG3-associated GO terms across cancer lineages are Otolith morphogenesis, Otolith development, and ATP synthesis coupled electron transport. Each is linked with LRIG3 in more than 13 cancer types. Because this analysis shows association rather than direction, both LRIG3-to-partner and partner-to-LRIG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Otolith morphogenesis grouped by LRIG3-low versus LRIG3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG3→partner) and Y-score (partner→LRIG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Otolith morphogenesis →	+1.575	+1.518	<.001	<.001	3	14
LUNG_SCLC	Otolith development →	+0.145	+1.720	<.001	<.001	3	12
OVARY	ATP synthesis coupled electron transport →	+0.090	+1.126	<.001	.001	3	10
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.090	+1.126	<.001	.001	3	10
OVARY	Proton motive force-driven ATP synthesis →	+0.092	+1.185	<.001	<.001	3	9
OVARY	Respiratory electron transport chain →	+0.079	+1.162	.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,172 associations by consensus.

Otolith morphogenesis by LRIG3 expression — KIDNEY

Explore this box plot interactively →