Across TCGA patient cohorts, LRIG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,931 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRIG2-associated proteins across cancer lineages are TRIM33, MFAP1, and RSBN1. Each is linked with LRIG2 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRIG2-to-partner and partner-to-LRIG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG2→partner) and Y-score (partner→LRIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRIM33 →	+0.345	+0.485	<.001	<.001	3	7
GBM	MFAP1 →	+0.263	+0.337	<.001	<.001	3	6
BRCA	RSBN1 →	+0.297	+0.481	<.001	<.001	3	6
PDAC	SF3B3 →	+0.168	+0.265	.001	.001	3	6
GBM	SRSF11 →	+0.209	+0.263	<.001	.006	3	6
LUAD	SDF2L1 →	-0.276	-0.303	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,931 associations by consensus.

Exploration

LRIG2 survival (RNA) · tumor vs normal (RNA) · all LRIG2 data types