Across TCGA patient cohorts, LRIG2 mutation is significantly associated with the RNA expression of many other genes, with 3,764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRIG2-associated genes across cancer lineages are RN7SL470P, RNU6-710P, and IFNWP9. Each is linked with LRIG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRIG2-to-partner and partner-to-LRIG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG2→partner) and Y-score (partner→LRIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL470P →	+0.168	+5.653	<.001	.003	3	4
SARC	RNU6-710P →	+0.473	+4.778	<.001	.006	3	3
BLCA	IFNWP9 →	+0.061	+4.033	<.001	.009	3	3
UCEC	SEPTIN7P14 →	+0.233	+1.913	.008	.003	3	3
UCEC	RNU6-1101P →	+0.173	+1.620	.004	.009	3	3
UCEC	LINC02210-CRHR1 →	+0.041	+1.841	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,764 associations by consensus.

Exploration

LRIG2 survival (RNA) · tumor vs normal (RNA) · all LRIG2 data types