LRIG2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, LRIG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,779 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRIG2-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription initiation, Negative regulation of transcription initiation by RNA polymerase II, and Epigenetic regulation of gene expression. Each is linked with LRIG2 in more than 17 cancer types. Because this analysis shows association rather than direction, both LRIG2-to-partner and partner-to-LRIG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRIG2→partner) and Y-score (partner→LRIG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENegative regulation of DNA-templated transcription initiation →+0.133+0.762<.001<.001318
SOFT_TISSUENegative regulation of transcription initiation by RNA polymerase II →+0.133+0.762<.001<.001318
BONEEpigenetic regulation of gene expression →+0.084+0.822<.001<.001317
UPPER_AERODIGESTIVE_TRACTTermination of RNA polymerase II transcription →+0.127+1.026<.001<.001317
UPPER_AERODIGESTIVE_TRACTHeterochromatin formation →+0.065+0.796<.001<.001316
BONENegative regulation of gene expression, epigenetic →+0.094+0.817<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,779 associations by consensus.

Exploration