LRFN4

Across TCGA patient cohorts, LRFN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,693 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRFN4-associated proteins across cancer lineages are DNMT1_S714, LIN54_S635, and NCAPG_S674. Each is linked with LRFN4 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRFN4-to-partner and partner-to-LRFN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRFN4 versus DNMT1_S714 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRFN4→partner) and Y-score (partner→LRFN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNMT1_S714 →	+0.604	+1.050	<.001	.001	3	6
HNSC	LIN54_S635 →	+0.573	+0.665	<.001	.007	3	6
LSCC	NCAPG_S674 →	+0.665	+0.754	<.001	<.001	3	5
LUAD	BUB1B_S543 →	+0.955	+0.973	.001	<.001	3	5
LUAD	ECT2_T359 →	+0.884	+0.586	<.001	<.001	3	5
LUAD	MKI67_S357 →	+0.845	+0.525	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,693 associations by consensus.

LRFN4 vs DNMT1_S714 — BRCA

Explore this scatter interactively →