LRFN4

Across TCGA cell cohorts, LRFN4 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRFN4-associated genes across cancer lineages are FABP12, GGTLC2, and OR51D1. Each is linked with LRFN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRFN4-to-partner and partner-to-LRFN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP12 grouped by LRFN4-low versus LRFN4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRFN4→partner) and Y-score (partner→LRFN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FABP12 →	+0.049	+2.979	<.001	.007	3	2
SKIN	GGTLC2 →	+0.035	+4.273	<.001	.006	3	1
LARGE_INTESTINE	OR51D1 →	+0.009	+4.217	<.001	.001	3	1
LARGE_INTESTINE	DCANP1 →	+0.010	+4.347	<.001	.001	3	1
BLOOD_Leukemia	CHRDL1 →	+1.426	+3.736	<.001	.001	3	1
BLOOD_Leukemia	PARD6A →	+1.034	+3.199	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

FABP12 by LRFN4 expression — BLOOD_Leukemia

Explore this box plot interactively →