LRFN1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRFN1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,673 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRFN1-associated genes across cancer lineages are TUBB1, SLC52A3, and RGCC. Each is linked with LRFN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRFN1-to-partner and partner-to-LRFN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRFN1 versus TUBB1 in GBM, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRFN1→partner) and Y-score (partner→LRFN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMTUBB1 →+0.336+0.191.008.00431
GBMSLC52A3 →+0.502+0.190.001.00331
GBMRGCC →+0.554+0.221.002.00131
GBMPLA2G4C →+0.615+0.231<.001<.00131
GBMTTC26 →-0.289-0.196.006<.00131
GBMC5 →-0.589-0.320<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,673 associations by consensus.

LRFN1 vs TUBB1 — GBM

Per-sample scatter of LRFN1 vs TUBB1 in GBM (Pearson r = 0.32).

Explore this scatter interactively →

Exploration