Across TCGA patient cohorts, LRCH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,770 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRCH3-associated proteins across cancer lineages are UBXN7, PAK2, and SERPINB1. Each is linked with LRCH3 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRCH3-to-partner and partner-to-LRCH3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRCH3→partner) and Y-score (partner→LRCH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UBXN7 →	+0.546	+0.560	<.001	<.001	3	6
OV	PAK2 →	+0.261	+0.639	.002	.003	2	7
HNSC	SERPINB1 →	-0.639	-0.672	<.001	<.001	3	5
GBM	SAE1 →	+0.304	+0.304	.003	.001	3	5
PDAC	ACTL6A →	+0.237	+0.301	.001	<.001	3	5
LSCC	ALG5 →	-0.450	-0.455	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,770 associations by consensus.

Exploration

LRCH3 survival (RNA) · tumor vs normal (RNA) · all LRCH3 data types