LRCH2

Across TCGA cell cohorts, LRCH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,299 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRCH2-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Inorganic anion transport. Each is linked with LRCH2 in more than 9 cancer types. Because this analysis shows association rather than direction, both LRCH2-to-partner and partner-to-LRCH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by LRCH2-low versus LRCH2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRCH2→partner) and Y-score (partner→LRCH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cytoplasmic translation →	+0.083	+1.412	<.001	.002	3	10
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+2.223	.001	<.001	3	10
LUNG_SCLC	Inorganic anion transport →	-0.056	-1.875	.001	<.001	3	9
STOMACH	Heterochromatin formation →	+0.076	+1.315	.001	.001	3	9
LUNG_SCLC	Spindle organization →	+0.060	+2.083	.001	<.001	3	9
OESOPHAGUS	Translational initiation →	+0.106	+0.678	<.001	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,299 associations by consensus.

Cytoplasmic translation by LRCH2 expression — OVARY

Explore this box plot interactively →