LRATD2

Across TCGA cell cohorts, LRATD2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LRATD2-associated genes across cancer lineages are SPATA48, CST9, and PROP1. Each is linked with LRATD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRATD2-to-partner and partner-to-LRATD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA48 grouped by LRATD2-low versus LRATD2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRATD2→partner) and Y-score (partner→LRATD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPATA48 →	+0.010	+5.247	<.001	<.001	3	1
LUNG_NSCLC_LUAD	CST9 →	+0.073	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	PROP1 →	+0.022	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	FAM187B →	+0.024	+3.760	.008	.008	3	1
LUNG_NSCLC_LUAD	CRYBA4 →	+0.058	+4.215	<.001	.002	3	1
LUNG_NSCLC_LUAD	GPR33 →	+0.016	+4.189	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

SPATA48 by LRATD2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →