LRAT

Across TCGA patient cohorts, LRAT protein abundance is significantly associated with the RNA expression of many other genes, with 551 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRAT-associated genes across cancer lineages are BSPRY, CDH13, and MIR8058. Each is linked with LRAT in more than 1 cancer types. Because this analysis shows association rather than direction, both LRAT-to-partner and partner-to-LRAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRAT versus BSPRY in BRCA, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRAT→partner) and Y-score (partner→LRAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BSPRY →	+1.131	+0.549	.009	<.001	3	2
LSCC	CDH13 →	-1.667	-0.604	<.001	.001	3	2
LSCC	MIR8058 →	-1.871	-0.613	.006	.001	3	2
LUAD	FOXRED2 →	-0.588	-0.620	.001	.006	3	1
LUAD	MXRA5 →	-1.569	-0.572	.001	.002	3	1
LUAD	FLT1 →	-0.931	-1.066	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 551 associations by consensus.

LRAT vs BSPRY — BRCA

Explore this scatter interactively →