LPO

Across TCGA patient cohorts, LPO RNA expression is significantly associated with the go_rna of many other GO terms, with 7,122 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LPO-associated GO terms across cancer lineages are Peptidyl-lysine modification, Golgi vesicle transport, and Establishment of protein localization to membrane. Each is linked with LPO in more than 17 cancer types. Because this analysis shows association rather than direction, both LPO-to-partner and partner-to-LPO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-lysine modification grouped by LPO-low versus LPO-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPO→partner) and Y-score (partner→LPO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Peptidyl-lysine modification →	+0.056	+0.228	<.001	<.001	3	18
ESCA	Golgi vesicle transport →	+0.068	+0.178	.001	.001	3	18
STAD	Establishment of protein localization to membrane →	+0.057	+0.189	<.001	<.001	3	18
STAD	Regulation of microtubule cytoskeleton organization →	+0.054	+0.182	<.001	<.001	3	18
STAD	Nucleus organization →	+0.062	+0.232	<.001	<.001	3	18
ESCA	Protein sumoylation →	+0.081	+0.226	<.001	<.001	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,122 associations by consensus.

Peptidyl-lysine modification by LPO expression — STAD

Explore this box plot interactively →