LPIN3

Across TCGA patient cohorts, LPIN3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,727 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LPIN3-associated genes across cancer lineages are ARHGAP15, PGK1, and DTHD1. Each is linked with LPIN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both LPIN3-to-partner and partner-to-LPIN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPIN3 versus ARHGAP15 in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPIN3→partner) and Y-score (partner→LPIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ARHGAP15 →	-1.040	-0.424	<.001	<.001	3	5
HNSC	PGK1 →	+0.798	+0.232	.001	.003	2	5
HNSC	DTHD1 →	-0.661	-0.368	.005	<.001	3	4
GBM	NEMP2 →	-0.439	-0.997	.003	.002	3	4
HNSC	CEP85L →	-0.581	-0.445	.001	<.001	3	4
COAD	SRGN →	-0.700	-0.371	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,727 associations by consensus.

LPIN3 vs ARHGAP15 — HNSC

Explore this scatter interactively →