LPGAT1

Across TCGA cell cohorts, LPGAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,194 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LPGAT1-associated GO terms across cancer lineages are Phosphatidylinositol acyl-chain remodeling, Phosphatidylglycerol acyl-chain remodeling, and Establishment of protein localization to endoplasmic reticulum membrane. Each is linked with LPGAT1 in more than 12 cancer types. Because this analysis shows association rather than direction, both LPGAT1-to-partner and partner-to-LPGAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol acyl-chain remodeling grouped by LPGAT1-low versus LPGAT1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPGAT1→partner) and Y-score (partner→LPGAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Phosphatidylinositol acyl-chain remodeling →	+0.207	+0.977	<.001	.001	3	13
STOMACH	Phosphatidylglycerol acyl-chain remodeling →	+0.221	+1.159	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to endoplasmic reticulum membrane →	+0.102	+1.126	<.001	<.001	3	11
SKIN	Intracellular magnesium ion homeostasis →	+0.080	+0.476	<.001	.001	2	11
BLOOD_Lymphoma	Peptidyl-serine modification →	+0.055	+1.000	<.001	.001	3	9
SOFT_TISSUE	Regulation of RNA export from nucleus →	+0.097	+0.794	.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,194 associations by consensus.

Phosphatidylinositol acyl-chain remodeling by LPGAT1 expression — OESOPHAGUS

Explore this box plot interactively →