LPGAT1-AS1

Across TCGA pan-cancer cohorts, LPGAT1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LPGAT1-AS1 data layer.

The strongest signal is observed in thymoma (THYM), where higher LPGAT1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LPGAT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and MESO show a favorable association.

THYM, BRCA, and MESO are the cancer types where LPGAT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.877	1.000	<.001	102	view →
BRCA	DFS	Median	All	0.586	0.489	.002	71	view →
MESO	DFS	Tertile	II,III,IV	0.428	0.204	.006	63	view →
DLBC	DFS	Tertile	III,IV	0.074	0.984	.003	57	view →
LIHC	OS	Median	II,III,IV	0.576	0.793	.004	52	view →
KIRC	OS	Median	All	0.536	0.683	<.001	45	view →
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	42	view →
LGG	DFS	Tertile	All	0.236	0.454	<.001	39	view →
OV	OS	Quartile	III,IV	0.757	0.652	.020	22	view →
KICH	DFS	Tertile	III,IV	0.035	0.772	.021	18	view →
THCA	OS	Quartile	All	0.939	0.992	.020	18	view →
SARC	DFS	Tertile	All	0.632	0.320	.013	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LPGAT1-AS1–THYM (OS)

Open the THYM breakdown →