LPCAT3

Across TCGA patient cohorts, LPCAT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,386 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LPCAT3-associated proteins across cancer lineages are PLEKHA5, CD9, and CMAS. Each is linked with LPCAT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both LPCAT3-to-partner and partner-to-LPCAT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPCAT3 versus PLEKHA5 in CCRCC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT3→partner) and Y-score (partner→LPCAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLEKHA5 →	+0.343	+0.498	<.001	<.001	3	6
OV	CD9 →	+0.980	+0.819	<.001	<.001	3	6
OV	CMAS →	+0.552	+0.650	<.001	<.001	3	6
LSCC	FKBP4 →	+0.559	+0.492	<.001	<.001	3	6
HNSC	USP5 →	+0.362	+0.565	<.001	.009	3	6
HNSC	PHB →	+0.425	+0.738	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,386 associations by consensus.

LPCAT3 vs PLEKHA5 — CCRCC

Explore this scatter interactively →