LPCAT3

Across TCGA cell cohorts, LPCAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,179 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LPCAT3-associated GO terms across cancer lineages are Chylomicron assembly, Positive regulation of intestinal absorption, and Positive regulation of intestinal lipid absorption. Each is linked with LPCAT3 in more than 18 cancer types. Because this analysis shows association rather than direction, both LPCAT3-to-partner and partner-to-LPCAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chylomicron assembly grouped by LPCAT3-low versus LPCAT3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT3→partner) and Y-score (partner→LPCAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Chylomicron assembly →	+0.300	+1.302	<.001	<.001	3	19
STOMACH	Positive regulation of intestinal absorption →	+0.472	+1.219	.003	<.001	3	18
STOMACH	Positive regulation of intestinal lipid absorption →	+0.472	+1.219	.003	<.001	3	18
OVARY	Regulation of intestinal cholesterol absorption →	+0.348	+0.896	.003	<.001	3	18
OVARY	Positive regulation of intestinal cholesterol absorption →	+0.316	+0.927	.003	<.001	3	18
KIDNEY	Regulation of sterol biosynthetic process →	+0.105	+0.932	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,179 associations by consensus.

Chylomicron assembly by LPCAT3 expression — SOFT_TISSUE

Explore this box plot interactively →