LPCAT2

Across TCGA pan-cancer cohorts, LPCAT2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LPCAT2 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LPCAT2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LPCAT2 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and HNSC are the cancer types where LPCAT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	III,IV	0.183	0.926	<.001	20	view →
UCEC	OS	Tertile	All	1.000	0.871	.012	12	view →
HNSC	OS	Median	III,IV	0.567	0.779	.032	2	view →
CCRCC	OS	Median	All	0.767	0.909	.031	1	view →
LSCC	OS	Median	II,III,IV	0.890	1.000	.034	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LPCAT2–LUAD (DFS)

Open the LUAD breakdown →