LPCAT2

Across TCGA patient cohorts, LPCAT2 mutation is significantly associated with the RNA expression of many other genes, with 1,893 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LPCAT2-associated genes across cancer lineages are AQP7P4, RNA5SP321, and PSAT1P4. Each is linked with LPCAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPCAT2-to-partner and partner-to-LPCAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P4 grouped by LPCAT2-low versus LPCAT2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT2→partner) and Y-score (partner→LPCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	AQP7P4 →	+0.071	+4.539	<.001	.008	3	2
CESC	RNA5SP321 →	+0.284	+4.539	<.001	.008	3	2
CESC	PSAT1P4 →	+0.116	+4.503	<.001	.005	3	2
SKCM	EIF4EBP2P3 →	+0.043	+4.039	<.001	.009	3	2
UCEC	PES1 →	+0.492	+3.807	.004	<.001	3	2
UCEC	KCTD9 →	+0.706	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,893 associations by consensus.

AQP7P4 by LPCAT2 expression — CESC

Explore this box plot interactively →