LPCAT2

Across TCGA cell cohorts, LPCAT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,935 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LPCAT2-associated GO terms across cancer lineages are Regulation of protein maturation, Regulation of protein processing, and Regulation of cell-matrix adhesion. Each is linked with LPCAT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both LPCAT2-to-partner and partner-to-LPCAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein maturation grouped by LPCAT2-low versus LPCAT2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT2→partner) and Y-score (partner→LPCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein maturation →	+0.235	+2.262	<.001	<.001	3	12
BREAST	Regulation of protein processing →	+0.141	+1.305	<.001	<.001	3	12
BREAST	Regulation of cell-matrix adhesion →	+0.079	+1.207	.004	.003	2	12
BONE	Trophoblast cell migration →	+0.299	+1.665	.003	.004	2	11
LUNG_NSCLC_LUSC	Maintenance of location in cell →	+0.085	+2.202	.001	.008	3	10
BONE	Negative regulation of plasminogen activation →	+1.213	+2.057	.002	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,935 associations by consensus.

Regulation of protein maturation by LPCAT2 expression — BONE

Explore this box plot interactively →