LPCAT1

Across TCGA patient cohorts, LPCAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,489 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LPCAT1-associated genes across cancer lineages are C5orf22, CLPTM1L, and CPED1. Each is linked with LPCAT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LPCAT1-to-partner and partner-to-LPCAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPCAT1 versus C5orf22 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT1→partner) and Y-score (partner→LPCAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C5orf22 →	+0.466	+0.309	.003	.002	3	6
LUAD	CLPTM1L →	+0.617	+0.415	<.001	<.001	3	5
UCEC	CPED1 →	-0.758	-0.474	.002	<.001	3	4
HNSC	PSMB2 →	+0.416	+0.323	.008	.005	3	4
LUAD	MTRR →	+0.498	+0.413	<.001	<.001	3	4
LUAD	NSUN2 →	+0.548	+0.435	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,489 associations by consensus.

LPCAT1 vs C5orf22 — HNSC

Explore this scatter interactively →