LPCAT1

Across TCGA cell cohorts, LPCAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,674 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LPCAT1-associated GO terms across cancer lineages are Nuclear export, Positive regulation of intracellular estrogen receptor signaling pathway, and Phosphatidylglycerol acyl-chain remodeling. Each is linked with LPCAT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LPCAT1-to-partner and partner-to-LPCAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by LPCAT1-low versus LPCAT1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT1→partner) and Y-score (partner→LPCAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Nuclear export →	+0.061	+1.338	<.001	<.001	3	8
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.102	+0.812	.005	.001	3	8
CNS	Phosphatidylglycerol acyl-chain remodeling →	+0.095	+0.934	.002	.001	3	7
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription termination →	+0.089	+1.265	<.001	<.001	3	7
BONE	tRNA transcription →	+0.113	+0.949	<.001	.002	3	7
OESOPHAGUS	Chromosome condensation →	+0.171	+1.133	.008	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,674 associations by consensus.

Nuclear export by LPCAT1 expression — PANCREAS

Explore this box plot interactively →