LPAR6

Across TCGA patient cohorts, LPAR6 mutation is significantly associated with the RNA expression of many other genes, with 734 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LPAR6-associated genes across cancer lineages are SNRPGP17, CWC27, and GGCT. Each is linked with LPAR6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPAR6-to-partner and partner-to-LPAR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP17 grouped by LPAR6-low versus LPAR6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR6→partner) and Y-score (partner→LPAR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SNRPGP17 →	+0.295	+2.764	<.001	.002	3	2
UCEC	CWC27 →	+0.568	+3.346	.004	.005	3	2
UCEC	GGCT →	+0.759	+3.354	<.001	.005	3	2
UCEC	RN7SL134P →	+0.152	+2.599	<.001	.003	3	2
COAD	MIR147A →	+0.486	+4.308	<.001	.009	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 734 associations by consensus.

SNRPGP17 by LPAR6 expression — BLCA

Explore this box plot interactively →