LPAR6

Across TCGA cell cohorts, LPAR6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,280 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LPAR6-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Response to vitamin B1, and Telomeric 3' overhang formation. Each is linked with LPAR6 in more than 6 cancer types. Because this analysis shows association rather than direction, both LPAR6-to-partner and partner-to-LPAR6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by LPAR6-low versus LPAR6-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR6→partner) and Y-score (partner→LPAR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fatty acid beta-oxidation →	+0.114	+1.862	.003	.001	3	7
SOFT_TISSUE	Response to vitamin B1 →	+0.135	+1.141	.003	.001	3	7
LUNG_NSCLC_LUAD	Telomeric 3' overhang formation →	-0.082	-1.266	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.131	+1.721	<.001	<.001	3	7
BREAST	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.074	+1.091	<.001	<.001	3	7
BLOOD_Lymphoma	Xenophagy →	+0.182	+1.645	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,280 associations by consensus.

Fatty acid beta-oxidation by LPAR6 expression — LIVER

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