Across TCGA patient cohorts, LPAR5 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LPAR5-associated genes across cancer lineages are GMP, CD8+ Tcm, and CD8+ Tem. Each is linked with LPAR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPAR5-to-partner and partner-to-LPAR5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR5→partner) and Y-score (partner→LPAR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GMP →	+0.105	+3.055	<.001	.005	3	2
HNSC	CD8+ Tcm →	+0.080	+3.813	<.001	.042	3	1
HNSC	CD8+ Tem →	+0.037	+6.954	<.001	.012	3	1
HNSC	Platelets →	+0.017	+4.100	.048	.029	3	1
HNSC	CD4+ T-cells →	+0.029	+4.936	<.001	.047	3	1
COAD	Melanocytes →	+0.024	+2.901	<.001	.032	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

LPAR5 survival (RNA) · tumor vs normal (RNA) · all LPAR5 data types