Across TCGA cell cohorts, LPAR5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LPAR5-associated genes across cancer lineages are REG1B, OR10W1, and FAM218A. Each is linked with LPAR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPAR5-to-partner and partner-to-LPAR5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR5→partner) and Y-score (partner→LPAR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	REG1B →	+1.746	+3.518	.004	.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.014	+3.562	<.001	.002	3	1
LARGE_INTESTINE	FAM218A →	+0.302	+2.906	.001	.008	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
LARGE_INTESTINE	KCNK17 →	+0.059	+2.906	.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

LPAR5 survival (RNA) · tumor vs normal (RNA) · all LPAR5 data types