LPAR4

Across TCGA cell cohorts, LPAR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,215 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LPAR4-associated GO terms across cancer lineages are Regulation of transcription elongation by RNA polymerase II, Regulation of mRNA processing, and Transcription initiation at RNA polymerase II promoter. Each is linked with LPAR4 in more than 6 cancer types. Because this analysis shows association rather than direction, both LPAR4-to-partner and partner-to-LPAR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription elongation by RNA polymerase II grouped by LPAR4-low versus LPAR4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR4→partner) and Y-score (partner→LPAR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of transcription elongation by RNA polymerase II →	+0.050	+0.433	<.001	.002	3	7
SOFT_TISSUE	Regulation of mRNA processing →	+0.079	+1.111	<.001	.001	3	6
BONE	Transcription initiation at RNA polymerase II promoter →	+0.069	+1.346	.001	<.001	3	6
SKIN	Malonyl-CoA catabolic process →	-1.045	-0.681	<.001	<.001	3	6
LARGE_INTESTINE	Cortisol metabolic process →	-0.690	-0.022	.003	.003	3	6
KIDNEY	Propionyl-CoA metabolic process →	-0.087	-0.427	.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,215 associations by consensus.

Regulation of transcription elongation by RNA polymerase II by LPAR4 expression — SKIN

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