LPAR3

Across TCGA patient cohorts, LPAR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,939 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LPAR3-associated proteins across cancer lineages are PLEKHA6_S459, KRT5, and KRT5_S77. Each is linked with LPAR3 in more than 3 cancer types. Because this analysis shows association rather than direction, both LPAR3-to-partner and partner-to-LPAR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPAR3 versus PLEKHA6_S459 in PDAC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR3→partner) and Y-score (partner→LPAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PLEKHA6_S459 →	-1.412	-0.975	<.001	<.001	3	4
PDAC	KRT5 →	+1.850	+0.953	<.001	<.001	3	4
PDAC	KRT5_S77 →	+2.254	+0.969	.001	<.001	3	4
LSCC	FAM110C_S202 →	+1.398	+1.438	<.001	<.001	3	4
LSCC	IRF6 →	+0.559	+0.987	<.001	<.001	3	4
HNSC	NDRG1 →	+0.903	+1.262	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,939 associations by consensus.

LPAR3 vs PLEKHA6_S459 — PDAC

Explore this scatter interactively →