LPAR3

Across TCGA patient cohorts, LPAR3 mutation is significantly associated with the RNA expression of many other genes, with 2,954 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LPAR3-associated genes across cancer lineages are GAGE2A, PIGW, and IGLVV-58. Each is linked with LPAR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both LPAR3-to-partner and partner-to-LPAR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE2A grouped by LPAR3-low versus LPAR3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR3→partner) and Y-score (partner→LPAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	GAGE2A →	+1.258	+3.828	.008	.009	3	3
UCEC	PIGW →	+0.595	+2.673	.001	<.001	3	2
BLCA	IGLVV-58 →	+0.383	+5.147	<.001	.003	3	2
BLCA	LSM6P2 →	+0.233	+5.017	.001	.002	3	2
SKCM	LINC02639 →	+0.235	+2.365	<.001	.007	3	2
LGG	SMARCE1P7 →	+0.077	+4.936	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,954 associations by consensus.

GAGE2A by LPAR3 expression — STAD

Explore this box plot interactively →