LPAR2

Across TCGA patient cohorts, LPAR2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,954 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LPAR2-associated genes across cancer lineages are LIX1L, MT2A, and VASN. Each is linked with LPAR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LPAR2-to-partner and partner-to-LPAR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPAR2 versus LIX1L in HNSC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR2→partner) and Y-score (partner→LPAR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LIX1L →	-0.891	-0.834	.007	<.001	3	3
OV	MT2A →	-1.798	-0.744	.002	.003	3	2
OV	VASN →	-1.211	-0.584	.008	.005	3	2
OV	MT1E →	-2.281	-0.648	.002	.001	3	2
OV	MARCO →	-1.695	-0.576	<.001	<.001	3	2
HNSC	HNRNPUL2 →	-0.781	-0.679	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,954 associations by consensus.

LPAR2 vs LIX1L — HNSC

Explore this scatter interactively →