Across TCGA patient cohorts, LPAR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,752 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LPAR1-associated proteins across cancer lineages are APCS, MAP1A, and COPZ2. Each is linked with LPAR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LPAR1-to-partner and partner-to-LPAR1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR1→partner) and Y-score (partner→LPAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APCS →	+0.956	+0.737	<.001	.001	3	7
HNSC	MAP1A →	+0.555	+0.665	<.001	.002	3	7
OV	COPZ2 →	+0.780	+0.913	<.001	<.001	3	7
OV	RASA3 →	+0.453	+0.830	.002	<.001	3	6
CCRCC	PALLD →	+0.600	+0.877	.001	.003	3	6
OV	PDLIM3 →	+0.723	+0.825	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,752 associations by consensus.

Exploration

LPAR1 survival (RNA) · tumor vs normal (RNA) · all LPAR1 data types