LOXHD1

Across TCGA cell cohorts, LOXHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,239 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LOXHD1-associated GO terms across cancer lineages are Mammary gland development, Oocyte growth, and Regulation of calcium ion export across plasma membrane. Each is linked with LOXHD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LOXHD1-to-partner and partner-to-LOXHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mammary gland development grouped by LOXHD1-low versus LOXHD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LOXHD1→partner) and Y-score (partner→LOXHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mammary gland development →	+0.131	+3.740	<.001	.005	3	5
BONE	Oocyte growth →	+0.175	+4.092	.002	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of calcium ion export across plasma membrane →	+0.063	+0.013	.004	.005	2	5
BLOOD_Leukemia	Proteoglycan catabolic process →	+0.054	+0.826	.004	.003	3	4
BLOOD_Leukemia	Negative regulation of nitric oxide biosynthetic process →	+0.104	+0.737	.001	.003	3	4
BLOOD_Leukemia	Positive regulation of viral entry into host cell →	+0.065	+0.841	.007	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,239 associations by consensus.

Mammary gland development by LOXHD1 expression — BONE

Explore this box plot interactively →