LONRF3

Across TCGA cell cohorts, LONRF3 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible LONRF3-associated genes across cancer lineages are SUPT20HL1, POTEB3, and OOSP4A. Each is linked with LONRF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LONRF3-to-partner and partner-to-LONRF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SUPT20HL1 grouped by LONRF3-low versus LONRF3-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LONRF3→partner) and Y-score (partner→LONRF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SUPT20HL1 →	+0.092	+4.807	<.001	.003	3	1
OVARY	POTEB3 →	+0.074	+4.700	<.001	.002	3	1
OVARY	OOSP4A →	+0.045	+4.029	.001	.009	3	1
CNS	OR13C2 →	+0.012	+5.754	<.001	.002	3	1
SKIN	SYT10 →	+0.327	+3.632	<.001	.003	3	1
SKIN	CRISP2 →	+0.208	+3.789	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

SUPT20HL1 by LONRF3 expression — OVARY

Explore this box plot interactively →