LONRF2

Across TCGA cell cohorts, LONRF2 mutation is significantly associated with the RNA expression of many other genes, with 309 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LONRF2-associated genes across cancer lineages are PRRG3, CALHM4, and CBY1. Each is linked with LONRF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LONRF2-to-partner and partner-to-LONRF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRRG3 grouped by LONRF2-low versus LONRF2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LONRF2→partner) and Y-score (partner→LONRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PRRG3 →	+0.460	+4.927	<.001	.001	3	1
BLOOD_Lymphoma	CALHM4 →	+0.375	+4.350	<.001	.005	3	1
LARGE_INTESTINE	CBY1 →	+0.693	+3.451	<.001	.002	3	1
LARGE_INTESTINE	MIOX →	+0.343	+3.364	<.001	.002	3	1
LARGE_INTESTINE	HMGXB4 →	+0.651	+3.364	<.001	.002	3	1
LARGE_INTESTINE	DESI1 →	+0.531	+3.169	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 309 associations by consensus.

PRRG3 by LONRF2 expression — BLOOD_Lymphoma

Explore this box plot interactively →