LONP2

Across TCGA cell cohorts, LONP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LONP2-associated GO terms across cancer lineages are Cytosolic transport, Phosphatidylinositol metabolic process, and Endosomal transport. Each is linked with LONP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both LONP2-to-partner and partner-to-LONP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by LONP2-low versus LONP2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LONP2→partner) and Y-score (partner→LONP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cytosolic transport →	+0.080	+0.798	.004	.008	3	15
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.053	+0.884	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.067	+0.785	<.001	.002	3	13
BREAST	Golgi to endosome transport →	+0.091	+0.658	<.001	<.001	3	13
KIDNEY	Peptidyl-serine phosphorylation →	+0.091	+0.782	<.001	.003	3	12
BLOOD_Lymphoma	Peptidyl-serine modification →	+0.072	+0.933	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,140 associations by consensus.

Cytosolic transport by LONP2 expression — KIDNEY

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